Projects

After hours, I like to hack together these homebrews:
Age‐standardised diabetes care continuum by race & sexual orientation
Prevalence, Monitoring, Treatment, and Control of Type 2 Diabetes by Race and Sexual Orientation Among Males with HIV
Jiali Guo, Samuel C.O. Opara, Sophia A. Hussen, Jithin Sam Varghese
type 2 diabetes HIV EHR cardiovascular disease health disparities

Summary

Our study utilized electronic health records (EHR) of an HIV outpatient clinic to assess the continuum of diabetes care among people with HIV (PWH) and explored potential disparities in the management of diabetes across different racial and sexual orientation groups. We observed higher crude prevalence among Black heterosexual men but no meaningful differences after adjusting for BMI.

Distribution of clinical characteristics residuals by cluster
Data-Driven Subtypes of Newly Diagnosed Youth-Onset Type 2 Diabetes in the USA
Jiali Guo, Zhongyu Li, Rodrigo M. Carrillo-Larco, Daniel S. Hsia, Jessica L Harding, Mohammed K. Ali, Jithin Sam Varghese
precision medicine diabetes phenotypes clustering analysis youth type 2 diabetes beta cell function insulin deficiency insulin resistance

Summary

Using data from the two largest studies on youth-onset type 2 diabetes, our study identified three data-driven subtypes with distinct clinical characteristics. These subtypes highlight the heterogeneity of youth-onset type 2 diabetes, offering opportunities for improved risk stratification and tailored disease management.